What dietary recommendation should be given to clients taking trimethoprim/sulfamethoxazole?

Clients taking trimethoprim/sulfamethoxazole should be advised to stay hydrated with adequate fluid intake. This recommendation is crucial because trimethoprim/sulfamethoxazole can lead to potential renal side effects, particularly crystalluria, which is the formation of crystals in the urine. Increased fluid intake helps dilute the urine and flush out the kidneys, minimizing the risk of crystallization and ensuring that the drug is effectively cleared from the body. Proper hydration is essential for maintaining kidney function and reducing the risk of kidney-related adverse effects associated with the medication.

Maintaining high fluid intake can also support overall health, especially in patients who may be at risk for dehydration due to illness or the effects of the medication. Therefore, the emphasis on hydration is a key aspect of dietary recommendations for these clients.