What effect does the medication prednisone have on the immune system?

Prednisone is a synthetic corticosteroid that has a significant impact on the immune system, primarily by suppressing immune responses. This suppression occurs because prednisone inhibits the action of inflammatory cells and the production of various cytokines, which are crucial for initiating and sustaining immune responses. By doing so, it reduces inflammation and alters the immune system's response to antigens, making it beneficial for treating autoimmune diseases and conditions characterized by excessive inflammation.

The suppression of the immune system can increase the risk of infections since the body becomes less capable of mounting an effective defense against pathogens. This is a critical aspect when considering long-term treatment with prednisone, as healthcare providers must monitor for signs of infection and other complications related to immunosuppression. Thus, understanding the immunosuppressive effects of prednisone is essential for its safe and effective use in clinical settings.