What important instruction should be given to a client prescribed famotidine for a gastric ulcer?

The instruction to "Report yellowing of the skin" is significant because it is a potential indicator of liver issues, such as hepatotoxicity, which can be associated with certain medications. While famotidine is generally considered safe and has a low incidence of serious side effects, monitoring for signs of liver dysfunction is important, especially in patients who may be at higher risk. Yellowing of the skin, or jaundice, can indicate elevated bilirubin levels due to liver problems, which requires immediate medical attention.

This vigilance in monitoring for adverse effects is essential in pharmacotherapy for gastric ulcers, as it ensures that the patient remains safe while receiving treatment and can help prevent complications related to liver function. Recognizing and reporting such symptoms can facilitate early intervention if necessary, which is critical in maintaining overall health while managing gastric conditions.